Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ACV24887.1TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: abu:Abu_1423 transcriptional regulatory protein HypF. (762 aa)    
Predicted Functional Partners:
ACV24444.1
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: afw:Anae109_0515 hydrogenase expression/formation protein HypE.
 
 
 0.986
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
       0.979
ACV25298.1
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: dal:Dalk_2011 hydrogenase expression/formation protein HypD.
 
  
 0.976
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.920
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
  
 
 0.898
ACV24304.1
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: wsu:WS0792 hydrogenase expression/formation protein.
  
 
 0.893
ACV24803.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: hch:HCH_00076 hydrogenase accessory protein HypB.
     
 0.873
ACV25051.1
Contains selenocysteine; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: gem:GM21_3972 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.860
ACV24079.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dps:DP1013 methylviologen-reducing hydrogenase, alpha chain.
 
 
 
 0.789
ACV25231.1
TIGRFAM: hydrogenase maturation protease HycI; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: ppd:Ppro_0598 hydrogenase maturation protease.
 
   
 0.761
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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