Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24892.1Protein of unknown function DUF367; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (167 aa)    
Predicted Functional Partners:
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
 
    0.964
ACV24890.1
PFAM: putative RNA methylase; THUMP domain protein; DNA methylase N-4/N-6 domain protein; KEGG: similar to tRNA guanosine-2-O-methyltransferase TRM11 homolog.
 
  
 0.734
eif6
Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
  
 0.664
ACV24331.1
Non-specific serine/threonine protein kinase; KEGG: RIOK2; RIO kinase 2 (yeast); K07179 RIO kinase 2; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART: protein of unknown function RIO1.
 
  
 0.616
ACV24804.1
KH domain protein; KEGG: RNA-binding protein; K06961; TIGRFAM: KH domain protein; PFAM: K Homology, type 1, subgroup; SMART: KH domain protein.
 
 
 0.604
ACV23921.1
TIGRFAM: small GTP-binding protein; PFAM: Nucleolar GTP-binding-1 domain protein; GTP-binding protein HSR1-related; Miro domain protein; KEGG: nucleolar GTP-binding protein.
 
  
 0.569
rps2
TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: RSP1; 40S ribosomal protein-like protein; K02998 small subunit ribosomal protein SAe; Belongs to the universal ribosomal protein uS2 family.
  
    0.565
ACV24891.1
TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ecp:ECP_1968 drug/sodium antiporter.
     
 0.563
ACV25197.1
PFAM: PUA domain containing protein; SMART: PUA domain containing protein; KEGG: TMA20; Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma22p; null mutant exhibits translation defects; has homology to human oncogene MCT-1; K07575 PUA do-TRUNCATED-.
  
     0.543
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: hypothetical protein; Belongs to the eukaryotic ribosomal protein eS1 family.
 
    0.540
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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