Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24919.1PFAM: CheC domain protein; KEGG: gem:GM21_0635 CheC, inhibitor of MCP methylation. (209 aa)    
Predicted Functional Partners:
ACV24920.1
PFAM: CheC domain protein; KEGG: gem:GM21_0635 CheC, inhibitor of MCP methylation.
 
 
 
0.998
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 0.995
ACV24921.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: ank:AnaeK_4453 response regulator receiver protein.
 
 
 0.984
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.834
ACV24459.1
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; SMART: Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; KEGG: nam:NAMH_0362 chemotaxis protein CheA.
 
  
 0.832
ACV25014.1
PFAM: Type II secretion system F domain.
 
  
 0.717
ACV24461.1
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: dma:DMR_10020 chemotaxis protein CheW.
  
  
 0.714
ACV25016.1
Flagella biogenesis ATPase-like protein; KEGG: bba:Bd2712 DNA repair protein RadA.
 
  
 0.682
ACV24465.1
PFAM: domain of unknown function DUF1745; KEGG: sat:SYN_01291 signal transduction histidine kinase.
  
     0.653
ACV25022.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
 
    0.631
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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