Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24928.1PFAM: Protein of unknown function DUF749. (106 aa)    
Predicted Functional Partners:
ACV24927.1
PFAM: Uncharacterized conserved protein UCP037052.
  
    0.996
ACV24929.1
PFAM: Protein of unknown function DUF2118.
       0.958
ACV23924.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: dma:DMR_13800 two-component hybrid sensor and regulator.
   
    0.827
ACV24930.1
PFAM: Polyprenyl synthetase; KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family.
       0.726
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
       0.565
ACV24933.1
KEGG: nis:NIS_0688 succinate dehydrogenase/fumarate reductase, subunit C; TIGRFAM: CoB/CoM heterodisulfide reductase, subunit B; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein.
       0.514
ACV23866.1
PFAM: UspA domain protein; KEGG: aci:ACIAD1238 hypothetical protein.
   
    0.500
ACV25195.1
PFAM: metallophosphoesterase; KEGG: dol:Dole_2142 metallophosphoesterase.
       0.417
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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