STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (359 aa)    
Predicted Functional Partners:
ACV24930.1
PFAM: Polyprenyl synthetase; KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.986
ACV24251.1
Aspartate/glutamate/uridylate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
 
  
 0.983
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
  
 0.921
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
  
    0.888
ACV24663.1
PFAM: aminotransferase class V; KEGG: ank:AnaeK_3093 aminotransferase class V.
  
 0.877
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
 0.791
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
 
 0.696
ACV24772.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: abu:Abu_1156 acetolactate synthase 3 catalytic subunit; Belongs to the TPP enzyme family.
 
 
 0.693
rps2
TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: RSP1; 40S ribosomal protein-like protein; K02998 small subunit ribosomal protein SAe; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.684
ACV24895.1
TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; KEGG: hypothetical protein; K00021 3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
   
 0.670
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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