Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24947.1PFAM: nucleoside recognition domain protein; KEGG: dat:HRM2_02300 hypothetical protein. (311 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
   
    0.803
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
       0.630
ACV25054.1
KEGG: hch:HCH_02741 hypothetical protein.
   
    0.606
ACV24946.1
PFAM: transcriptional regulator PadR family protein; KEGG: scl:sce3089 PadR family transcriptional regulator.
  
    0.605
ACV24945.1
KEGG: gsu:GSU0011 ABC transporter, ATP-binding protein; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.568
ACV24944.1
TIGRFAM: daunorubicin resistance ABC transporter, inner membrane subunit B; PFAM: ABC-2 type transporter; KEGG: sat:SYN_01665 ABC-type multidrug transport system, permease component.
       0.554
ACV24360.1
PFAM: DEAD/DEAH box helicase domain protein; Protein of unknown function DUF1998; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dal:Dalk_2442 DEAD/DEAH box helicase domain protein.
  
    0.521
ACV24866.1
KEGG: dde:Dde_1794 hypothetical protein.
  
     0.519
ACV24383.1
PFAM: beta-lactamase domain protein; KEGG: hypothetical protein.
 
    0.493
ACV23851.1
PFAM: polysaccharide biosynthesis protein; multi antimicrobial extrusion protein MatE; KEGG: pcr:Pcryo_0621 polysaccharide biosynthesis protein.
  
    0.451
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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