Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24982.1PFAM: protein of unknown function DUF98; KEGG: sde:Sde_3289 hypothetical protein. (167 aa)    
Predicted Functional Partners:
ACV24983.1
PFAM: Radical SAM domain protein; KEGG: sat:SYN_01240 pyruvate formate-lyase activating enzyme.
  
    0.970
ACV24981.1
PFAM: peptidase M24; creatinase; KEGG: dps:DP0126 Xaa-Pro dipeptidase.
       0.880
ACV23857.1
TIGRFAM: methanogenesis marker protein 12; Belongs to the UPF0285 family.
  
     0.622
ACV24041.1
TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; PFAM: CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit.
  
     0.594
ACV25166.1
PFAM: Protein of unknown function DUF166; KEGG: dal:Dalk_4871 protein of unknown function DUF166.
  
     0.588
ACV24984.1
PFAM: AMMECR1 domain protein; KEGG: ppd:Ppro_3512 AMMECR1 domain-containing protein.
       0.584
ACV24464.1
UbiA prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.582
ACV24748.1
PFAM: Protein of unknown function DUF166; KEGG: dal:Dalk_4871 protein of unknown function DUF166.
  
     0.563
ACV25187.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
  
     0.561
ACV24036.1
PFAM: Protein of unknown function DUF128; Ribonuclease R winged-helix domain protein; KEGG: sat:SYN_03243 putative cytoplasmic protein.
  
     0.554
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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