Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24983.1PFAM: Radical SAM domain protein; KEGG: sat:SYN_01240 pyruvate formate-lyase activating enzyme. (333 aa)    
Predicted Functional Partners:
ACV24984.1
PFAM: AMMECR1 domain protein; KEGG: ppd:Ppro_3512 AMMECR1 domain-containing protein.
     0.978
ACV24982.1
PFAM: protein of unknown function DUF98; KEGG: sde:Sde_3289 hypothetical protein.
  
    0.970
ACV24993.1
PFAM: protein of unknown function DUF52; KEGG: pca:Pcar_1651 dioxygenase; Belongs to the MEMO1 family.
     0.922
ACV24740.1
KEGG: sat:SYN_01979 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
  
  
 0.682
ACV24602.1
KEGG: hypothetical protein.
       0.609
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.609
ACV24250.1
PFAM: PHP domain protein; KEGG: gur:Gura_2545 hypothetical protein.
       0.587
ACV24774.1
PFAM: conserved hypothetical protein; KEGG: geo:Geob_3377 hypothetical protein.
       0.581
ACV24981.1
PFAM: peptidase M24; creatinase; KEGG: dps:DP0126 Xaa-Pro dipeptidase.
       0.513
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.484
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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