Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACV25033.1PFAM: Protein of unknown function DUF361. (75 aa)    
Predicted Functional Partners:
ACV25032.1
KEGG: ftn:FTN_0494 hypothetical protein.
       0.901
ACV25035.1
Hypothetical protein.
     
 0.794
ACV25034.1
PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: gem:GM21_2431 FG-GAP repeat protein.
       0.773
ACV25030.1
Hypothetical protein.
     
 0.724
ACV25029.1
KEGG: hypothetical protein.
     
 0.713
ACV25031.1
KEGG: hypothetical protein.
     
 0.644
ACV25036.1
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: cct3; chaperonin subunit 3 (gamma); K09495 T-complex protein 1 subunit gamma.
       0.463
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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