| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACV24264.1 | dacZ | Mefer_0438 | Mefer_1230 | TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: ppr:PBPRB0776 putative adenylate cyclase CyaB. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.658 |
| ACV24997.1 | dacZ | Mefer_1188 | Mefer_1230 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: tcx:Tcr_1677 phosphomannomutase; Belongs to the phosphohexose mutase family. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.815 |
| ACV24997.1 | nadK | Mefer_1188 | Mefer_0065 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: tcx:Tcr_1677 phosphomannomutase; Belongs to the phosphohexose mutase family. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.821 |
| ACV25041.1 | ACV25042.1 | Mefer_1232 | Mefer_1233 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: abu:Abu_0614 hypothetical protein. | PFAM: Helix-turn-helix type 11 domain protein. | 0.985 |
| ACV25041.1 | dacZ | Mefer_1232 | Mefer_1230 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: abu:Abu_0614 hypothetical protein. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.637 |
| ACV25041.1 | leuC-2 | Mefer_1232 | Mefer_1231 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: abu:Abu_0614 hypothetical protein. | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.874 |
| ACV25042.1 | ACV25041.1 | Mefer_1233 | Mefer_1232 | PFAM: Helix-turn-helix type 11 domain protein. | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: abu:Abu_0614 hypothetical protein. | 0.985 |
| ACV25042.1 | dacZ | Mefer_1233 | Mefer_1230 | PFAM: Helix-turn-helix type 11 domain protein. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.637 |
| ACV25042.1 | leuC-2 | Mefer_1233 | Mefer_1231 | PFAM: Helix-turn-helix type 11 domain protein. | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.874 |
| ACV25134.1 | dacZ | Mefer_1325 | Mefer_1230 | PFAM: TrkA-N domain protein; phosphoesterase DHHA1; phosphoesterase RecJ domain protein; KEGG: dol:Dole_0370 phosphoesterase domain-containing protein. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.643 |
| dacZ | ACV24264.1 | Mefer_1230 | Mefer_0438 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: ppr:PBPRB0776 putative adenylate cyclase CyaB. | 0.658 |
| dacZ | ACV24997.1 | Mefer_1230 | Mefer_1188 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: tcx:Tcr_1677 phosphomannomutase; Belongs to the phosphohexose mutase family. | 0.815 |
| dacZ | ACV25041.1 | Mefer_1230 | Mefer_1232 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: abu:Abu_0614 hypothetical protein. | 0.637 |
| dacZ | ACV25042.1 | Mefer_1230 | Mefer_1233 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | PFAM: Helix-turn-helix type 11 domain protein. | 0.637 |
| dacZ | ACV25134.1 | Mefer_1230 | Mefer_1325 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | PFAM: TrkA-N domain protein; phosphoesterase DHHA1; phosphoesterase RecJ domain protein; KEGG: dol:Dole_0370 phosphoesterase domain-containing protein. | 0.643 |
| dacZ | glmM | Mefer_1230 | Mefer_0779 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.819 |
| dacZ | hisC | Mefer_1230 | Mefer_0844 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Allinase-like; aminotransferase class V; KEGG: dal:Dalk_0935 histidinol-phosphate aminotransferase. | 0.645 |
| dacZ | leuC-2 | Mefer_1230 | Mefer_1231 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.851 |
| dacZ | nadK | Mefer_1230 | Mefer_0065 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.858 |
| dacZ | rpl37ae | Mefer_1230 | Mefer_1378 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Ribosomal protein L37a; Binds to the 23S rRNA. | 0.629 |