Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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[Homology]
Score
ACV25050.1TIGRFAM: coenzyme F420-reducing hydrogenase delta subunit; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: sfu:Sfum_2220 hydrogenase maturation protease. (179 aa)    
Predicted Functional Partners:
ACV25049.1
TIGRFAM: coenzyme F420 hydrogenase, subunit gamma; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfu:Sfum_2715 NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.999
ACV25051.1
Contains selenocysteine; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: gem:GM21_3972 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 0.994
ACV25048.1
TIGRFAM: coenzyme F420 hydrogenase, subunit beta; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: dal:Dalk_4964 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein.
 
 
 0.993
ACV24016.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2982 coenzyme F420 hydrogenase.
 
 
 0.931
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
  
 0.926
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
   
 
 0.924
ACV23946.1
TIGRFAM: coenzyme F420-reducing hydrogenase delta subunit; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: sfu:Sfum_2220 hydrogenase maturation protease.
  
  
 
0.904
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.537
ACV25047.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: vap:Vapar_5615 fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
     
 0.485
ACV24079.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dps:DP1013 methylviologen-reducing hydrogenase, alpha chain.
  
 
 0.428
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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