Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
corAMagnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (317 aa)    
Predicted Functional Partners:
srp19
Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
  
    0.971
ACV25063.1
PFAM: Protein of unknown function DUF373.
 
    0.867
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.675
ACV25062.1
PFAM: PKD domain containing protein; Protein of unknown function DUF361; SMART: PKD domain containing protein; KEGG: sde:Sde_3605 glycosyl hydrolase family chitinase.
 
     0.525
ACV23885.1
PFAM: sodium/hydrogen exchanger; KEGG: fph:Fphi_1574 monovalent cation:proton antiporter family protein.
 
  
 0.454
ACV25217.1
TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: gur:Gura_1454 PfpI family intracellular peptidase.
 
  
 0.424
ACV25000.1
TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: lpc:LPC_1520 cation efflux family protein.
 
  
 0.423
ACV25230.1
PFAM: phosphate transporter; KEGG: sse:Ssed_0370 phosphate transporter.
  
  
 0.400
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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