close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV25112.1PFAM: Zinc ribbon NADH pyrophosphatase; KEGG: dal:Dalk_0300 response regulator receiver protein. (191 aa)    
Predicted Functional Partners:
ACV25113.1
Hypothetical protein.
       0.881
ACV25010.1
PFAM: Methyltransferase type 12; Methyltransferase type 11; KEGG: dat:HRM2_44560 UbiE6.
 
     0.597
ACV24064.1
S-layer domain protein-like protein.
  
     0.590
ACV24849.1
Transcriptional regulator, MarR family; PFAM: regulatory protein ArsR; regulatory protein MarR; SMART: regulatory protein ArsR; KEGG: ank:AnaeK_0686 general secretion pathway protein-related protein.
  
     0.587
ACV25016.1
Flagella biogenesis ATPase-like protein; KEGG: bba:Bd2712 DNA repair protein RadA.
 
     0.574
ACV25014.1
PFAM: Type II secretion system F domain.
 
     0.571
ACV25024.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
 
     0.553
ACV25013.1
PFAM: Peptidase A24B, FlaK domain protein; peptidase A24A prepilin type IV; KEGG: shl:Shal_2284 peptidase A24A prepilin type IV.
  
     0.545
ACV25022.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
 
     0.543
ACV25114.1
PFAM: ATP dependent DNA ligase; KEGG: noc:Noc_1413 ATP-dependent DNA ligase.
       0.541
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.