Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV25114.1PFAM: ATP dependent DNA ligase; KEGG: noc:Noc_1413 ATP-dependent DNA ligase. (390 aa)    
Predicted Functional Partners:
ACV24657.1
Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.895
ACV24403.1
PFAM: Protein of unknown function DUF61; Belongs to the UPF0216 family.
  
     0.626
ACV24402.1
PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: acp:A2cp1_3392 protein of unknown function DUF190.
       0.609
ACV25327.1
PFAM: elongation factor Tu domain 2 protein; KEGG: cco:CCC13826_0756 selenocysteine-specific translation elongation factor.
       0.602
ACV25272.1
KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein.
 
    0.547
ACV25112.1
PFAM: Zinc ribbon NADH pyrophosphatase; KEGG: dal:Dalk_0300 response regulator receiver protein.
       0.543
ACV25115.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dal:Dalk_1379 binding-protein-dependent transport systems inner membrane component.
       0.541
ACV25113.1
Hypothetical protein.
       0.539
rpl10e
TIGRFAM: ribosomal protein L10.e; PFAM: Ribosomal protein L10e/L16; KEGG: 60S ribosomal protein L10; K02866 large subunit ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
       0.501
ACV25166.1
PFAM: Protein of unknown function DUF166; KEGG: dal:Dalk_4871 protein of unknown function DUF166.
  
     0.486
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.