Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ACV25116.1PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gur:Gura_3876 ABC transporter related. (257 aa)    
Predicted Functional Partners:
ACV23988.1
KEGG: dal:Dalk_1380 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components.
 
 0.999
ACV25115.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dal:Dalk_1379 binding-protein-dependent transport systems inner membrane component.
 
 0.999
ACV24063.1
PFAM: protein of unknown function DUF214; KEGG: pca:Pcar_0817 ABC-type transport system, permease component.
     0.914
ACV24428.1
PFAM: nitrogen regulatory protein P-II; KEGG: abu:Abu_0198 nitrogen regulatory protein PII; Belongs to the P(II) protein family.
   
 
 0.706
ACV24968.1
TIGRFAM: NifC-like ABC-type porter; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dat:HRM2_01690 putative molybdenum ABC-type transporter, permease subunit.
 
  
 0.613
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
  
 0.606
ACV24046.1
Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein.
       0.582
gatA
glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
     
 0.428
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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