Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ecfACobalt ABC transporter, ATPase subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (279 aa)    
Predicted Functional Partners:
ACV25151.1
TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: gbm:Gbem_3806 cobalt ABC transporter, inner membrane subunit CbiQ.
 
 0.999
ACV24361.1
TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: gem:GM21_2003 cobalt ABC transporter, inner membrane subunit CbiQ.
 
 0.992
cbiN
Cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
 
 
 0.988
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
 
 
 0.987
ACV24363.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: lhk:LHK_01045 cobalamin (vitamin B12) biosynthesis CbiM protein.
 
 
 0.944
ACV25330.1
PFAM: BioY protein; KEGG: mxa:MXAN_2207 BioY family protein.
 
 
 
 0.919
ACV24967.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dat:HRM2_01680 putative molybdenum ABC-type transporter, ATP-binding protein.
 
    
0.906
ACV24063.1
PFAM: protein of unknown function DUF214; KEGG: pca:Pcar_0817 ABC-type transport system, permease component.
      0.880
ACV24362.1
Hypothetical protein; KEGG: gur:Gura_0780 cobalamin (vitamin B12) biosynthesis CbiM protein.
  
 
 0.870
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
  
 0.766
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (20%) [HD]