Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25157.1PFAM: protein of unknown function UPF0047; KEGG: pca:Pcar_0621 hypothetical protein. (135 aa)    
Predicted Functional Partners:
ACV25156.1
PFAM: NADPH-dependent FMN reductase; KEGG: dps:DP1259 iron-sulfur flavoprotein.
       0.911
ACV24890.1
PFAM: putative RNA methylase; THUMP domain protein; DNA methylase N-4/N-6 domain protein; KEGG: similar to tRNA guanosine-2-O-methyltransferase TRM11 homolog.
       0.598
adkA
KEGG: bcs:BCAN_A0739 adenylate kinase.
       0.513
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.501
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
       0.477
ACV25154.1
PFAM: DNA polymerase beta domain protein region; KEGG: mca:MCA2732 hypothetical protein.
       0.443
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
       0.424
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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