Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25184.1PFAM: Ribosome maturation protein SBDS-like; KEGG: hypothetical protein, conserved. (235 aa)    
Predicted Functional Partners:
rpl37ae
Ribosomal protein L37a; Binds to the 23S rRNA.
  
   0.999
rpl18a
PFAM: Ribosomal LX protein.
  
 
 0.979
rpoP
RNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
    0.970
rpl14e
KEGG: hypothetical protein; K02875 large subunit ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family.
  
 
 0.962
ACV25187.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
  
 
 0.960
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
 
 0.948
rpl15e
PFAM: Ribosomal protein L15e; KEGG: 60S ribosomal protein L15 (RPL15B); K02877 large subunit ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
 0.945
ACV25188.1
PFAM: Protein of unknown function DUF2144.
       0.936
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
 
 
 0.923
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.909
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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