Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rpl37aeRibosomal protein L37a; Binds to the 23S rRNA. (92 aa)    
Predicted Functional Partners:
ACV25184.1
PFAM: Ribosome maturation protein SBDS-like; KEGG: hypothetical protein, conserved.
  
   0.999
rpl18a
PFAM: Ribosomal LX protein.
  
 
 0.999
rps4e
PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: Hypothetical protein CBG05762; K02987 small subunit ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
 
 
 0.998
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.998
rpl15e
PFAM: Ribosomal protein L15e; KEGG: 60S ribosomal protein L15 (RPL15B); K02877 large subunit ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
 0.998
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
  
 0.997
rpl21e
PFAM: Ribosomal protein L21e; KEGG: 60S ribosomal protein L21; K02889 large subunit ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
 
 0.997
rpl18
Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.997
rpl19e
Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
 0.997
rps6e
PFAM: Ribosomal protein S6e; KEGG: 40S ribosomal protein S6; K02991 small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.996
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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