Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25187.1Brix domain protein; Probably involved in the biogenesis of the ribosome. (169 aa)    
Predicted Functional Partners:
rpl18a
PFAM: Ribosomal LX protein.
  
   0.995
rpoP
RNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
    0.990
rpl37ae
Ribosomal protein L37a; Binds to the 23S rRNA.
 
 
   0.981
ACV25188.1
PFAM: Protein of unknown function DUF2144.
  
    0.980
ACV23918.1
PFAM: Protein of unknown function UPF0113.
   
 
 0.970
ACV25184.1
PFAM: Ribosome maturation protein SBDS-like; KEGG: hypothetical protein, conserved.
  
 
 0.960
rps8e
TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: rps8-1; 40S ribosomal protein S8; K02995 small subunit ribosomal protein S8e.
   
 
 0.951
rpl30
TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: 60S RIBOSOMAL PROTEIN L7; K02937 large subunit ribosomal protein L7e.
  
 
 0.947
ACV23949.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: SnoRNA binding domain containing protein.
  
 
 0.941
ACV23921.1
TIGRFAM: small GTP-binding protein; PFAM: Nucleolar GTP-binding-1 domain protein; GTP-binding protein HSR1-related; Miro domain protein; KEGG: nucleolar GTP-binding protein.
   
 
 0.931
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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