Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25215.1Uncharacterized Zn-finger protein-like protein; KEGG: PCGF6; polycomb group ring finger 6; K11470 polycomb group RING finger protein 6. (202 aa)    
Predicted Functional Partners:
rps2
TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: RSP1; 40S ribosomal protein-like protein; K02998 small subunit ribosomal protein SAe; Belongs to the universal ribosomal protein uS2 family.
  
    0.994
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: hypothetical protein; Belongs to the eukaryotic ribosomal protein eS1 family.
 
    0.994
rpl7ae
Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
    0.948
ACV24432.1
TRNA methyltransferase; KEGG: ATCHX11 (cation/H+ exchanger 11); monovalent cation:proton antiporter.
  
    0.902
rps12
Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
    0.897
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
    0.894
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
   
    0.891
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
   
    0.891
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
    0.890
rps28e
PFAM: Ribosomal protein S28e; KEGG: 40S ribosomal protein S28; K02979 small subunit ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
    0.887
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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