Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25259.1PFAM: cation transporter; KEGG: nam:NAMH_0238 K+ transporter trk. (472 aa)    
Predicted Functional Partners:
ACV23861.1
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: lip:LI0774 potassium transporter peripheral membrane component.
 
 
 0.989
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.742
pgk2
PFAM: ATP-cone domain protein; KEGG: hypothetical protein.
       0.728
ACV25262.1
PFAM: LOR/SDH bifunctional protein conserved domain protein; KEGG: pca:Pcar_2163 hypothetical protein.
       0.689
ACV25261.1
PFAM: Protein of unknown function DUF2100; KEGG: Ras guanine nucleotide exchange factor.
       0.688
map
Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
       0.609
ACV24426.1
PFAM: sodium/hydrogen exchanger; KEGG: cja:CJA_2911 putative pH regulated Na(+)/H(+) antiporter.
 
 
 0.582
ACV25263.1
PFAM: protein of unknown function UPF0153; KEGG: pca:Pcar_1310 hypothetical protein.
       0.476
ACV24394.1
PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; KEGG: gem:GM21_3877 TrkA-N domain protein.
     
 0.475
ACV24448.1
TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: sbp:Sbal223_3834 anion transporter.
  
  
 0.454
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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