Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pgk2PFAM: ATP-cone domain protein; KEGG: hypothetical protein. (310 aa)    
Predicted Functional Partners:
ACV25261.1
PFAM: Protein of unknown function DUF2100; KEGG: Ras guanine nucleotide exchange factor.
  
    0.981
ACV25262.1
PFAM: LOR/SDH bifunctional protein conserved domain protein; KEGG: pca:Pcar_2163 hypothetical protein.
  
    0.966
ACV25259.1
PFAM: cation transporter; KEGG: nam:NAMH_0238 K+ transporter trk.
       0.728
ACV23944.1
PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: phosphosulfolactate synthase.
      
 0.640
apgM
Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
   
 0.524
ACV25263.1
PFAM: protein of unknown function UPF0153; KEGG: pca:Pcar_1310 hypothetical protein.
       0.518
ACV25137.1
PFAM: Queuosine synthesis-like; KEGG: cjd:JJD26997_1992 hypothetical protein.
  
     0.512
ACV23943.1
KEGG: scl:sce7306 hypothetical protein.
      
 0.453
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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