Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25262.1PFAM: LOR/SDH bifunctional protein conserved domain protein; KEGG: pca:Pcar_2163 hypothetical protein. (422 aa)    
Predicted Functional Partners:
ACV25261.1
PFAM: Protein of unknown function DUF2100; KEGG: Ras guanine nucleotide exchange factor.
  
    0.977
pgk2
PFAM: ATP-cone domain protein; KEGG: hypothetical protein.
  
    0.966
ACV25259.1
PFAM: cation transporter; KEGG: nam:NAMH_0238 K+ transporter trk.
       0.689
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
      
 0.640
ACV24957.1
PFAM: amino acid-binding ACT domain protein.
  
     0.528
ACV25263.1
PFAM: protein of unknown function UPF0153; KEGG: pca:Pcar_1310 hypothetical protein.
       0.528
ACV23985.1
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: ilo:IL1212 agmatinase; Belongs to the arginase family.
     
 0.439
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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