Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25268.1Hypothetical protein; KEGG: abu:Abu_0940 adhesin/hemagglutinin. (458 aa)    
Predicted Functional Partners:
ACV25267.1
Conserved hypothetical protein.
       0.741
ACV25269.1
PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein.
       0.589
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
       0.442
ACV25271.1
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: bja:blr2308 putative molybdopterin biosynthesis protein.
       0.442
ACV25272.1
KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein.
       0.442
ACV25266.1
TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sat:SYN_02055 rRNA methylase.
       0.419
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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