Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pfdBPrefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (113 aa)    
Predicted Functional Partners:
pfdA
Prefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.987
ACV25302.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: abu:Abu_2037 exopolyphosphatase-related protein.
       0.933
rpoP
RNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
  
 0.916
ACV25036.1
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: cct3; chaperonin subunit 3 (gamma); K09495 T-complex protein 1 subunit gamma.
  
 0.901
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 
 0.855
rpl37ae
Ribosomal protein L37a; Binds to the 23S rRNA.
  
  
 0.837
ACV24469.1
PFAM: formate/nitrite transporter; KEGG: sat:SYN_01200 formate/nitrite transporter family protein.
    
 
 0.829
ACV25184.1
PFAM: Ribosome maturation protein SBDS-like; KEGG: hypothetical protein, conserved.
 
  
 0.811
rpl21e
PFAM: Ribosomal protein L21e; KEGG: 60S ribosomal protein L21; K02889 large subunit ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
  
 0.765
ACV24431.1
PFAM: DNA-binding TFAR19-related protein; KEGG: hypothetical protein; K06875; Belongs to the PDCD5 family.
  
   0.759
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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