fit to screen
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV25306.1PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; KEGG: bas:BUsg426 hypothetical protein. (500 aa)    
Predicted Functional Partners:
ACV24796.1
TIGRFAM: siroheme synthase; PFAM: TrkA-N domain protein; KEGG: tdn:Suden_1977 siroheme synthase CysG.
     
 0.885
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.771
ACV24876.1
PFAM: 4-vinyl reductase 4VR; KEGG: ppd:Ppro_0428 4-vinyl reductase, 4VR.
 
  
 0.721
ACV24687.1
PFAM: 4-vinyl reductase 4VR; Roadblock/LC7 family protein; KEGG: dat:HRM2_39440 hypothetical protein.
 
  
 0.655
ACV25307.1
KEGG: dol:Dole_0391 biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein.
  
    0.581
ACV24926.1
PFAM: 4-vinyl reductase 4VR.
  
  
 0.553
ACV25308.1
PFAM: Cupin 2 conserved barrel domain protein; KEGG: dvm:DvMF_2629 cupin 2 conserved barrel domain protein.
       0.532
ACV25305.1
PFAM: Xanthine/uracil/vitamin C permease; KEGG: lhk:LHK_00455 probable membrane permease protein.
       0.497
ACV25359.1
Hypothetical protein; KEGG: eea-1; EEA1 (Early Endosome Antigen, Rab effector) homolog; K12478 early endosome antigen 1.
  
     0.462
ACV25164.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: dal:Dalk_3856 radical SAM domain protein.
 
  
 0.442
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.