Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25311.1PFAM: Xylose isomerase domain protein TIM barrel; KEGG: gur:Gura_4159 xylose isomerase domain-containing protein. (251 aa)    
Predicted Functional Partners:
ACV25312.1
PFAM: protein of unknown function DUF105; KEGG: ppd:Ppro_1230 hypothetical protein.
 
     0.974
ACV24073.1
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: pca:Pcar_3128 hypothetical protein.
 
     0.543
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.541
ACV25122.1
PFAM: PfkB domain protein; KEGG: mmb:Mmol_0491 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.459
ACV25309.1
PFAM: Protein of unknown function DUF131.
       0.458
ACV24371.1
PFAM: Protein of unknown function DUF54; KEGG: hypothetical protein; Belongs to the UPF0201 family.
 
    0.405
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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