Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
ACV25331.1PFAM: protein of unknown function DUF1284; KEGG: wpi:WPa_0955 hypothetical protein. (132 aa)    
Predicted Functional Partners:
ACV25330.1
PFAM: BioY protein; KEGG: mxa:MXAN_2207 BioY family protein.
 
    0.833
ACV25332.1
PFAM: protein of unknown function UPF0132; KEGG: hha:Hhal_1506 hypothetical protein.
       0.686
ACV25328.1
PFAM: ApbE family lipoprotein; KEGG: sfu:Sfum_2124 hypothetical protein; Belongs to the UPF0280 family.
       0.534
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
       0.534
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
       0.493
ACV25327.1
PFAM: elongation factor Tu domain 2 protein; KEGG: cco:CCC13826_0756 selenocysteine-specific translation elongation factor.
       0.479
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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