Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25342.1TIGRFAM: L-seryl-tRNA(Sec) kinase; PFAM: Chromatin associated protein KTI12; KEGG: hypothetical protein. (248 aa)    
Predicted Functional Partners:
ACV24060.1
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family.
  
  
 0.984
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
  
 
 0.931
ACV24959.1
Histone acetyltransferase, ELP3 family; KEGG: hypothetical protein; K07739 elongator complex protein 3; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: Radical SAM domain protein; GCN5-related N-acetyltransferase; SMART: Elongator protein 3/MiaB/NifB.
  
 
 0.903
ACV24037.1
TIGRFAM: pyridoxal phosphate enzyme; KEGG: spl:Spea_0442 selenocysteine synthase.
     
  0.900
ACV24535.1
TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; GTP-binding protein HSR1-related; KEGG: hypothetical protein.
 
   
 0.716
vapC
PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
   
    0.698
ACV24804.1
KH domain protein; KEGG: RNA-binding protein; K06961; TIGRFAM: KH domain protein; PFAM: K Homology, type 1, subgroup; SMART: KH domain protein.
   
    0.625
ACV25340.1
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: nam:NAMH_1523 thioredoxin-disulfide reductase.
       0.580
ACV25187.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
  
    0.569
ACV25341.1
KEGG: hypothetical protein.
       0.562
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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