Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV25359.1Hypothetical protein; KEGG: eea-1; EEA1 (Early Endosome Antigen, Rab effector) homolog; K12478 early endosome antigen 1. (837 aa)    
Predicted Functional Partners:
ACV25358.1
Hypothetical protein.
       0.773
ACV25360.1
Hypothetical protein.
       0.752
ACV25067.1
PFAM: zinc/iron permease; KEGG: transmembrane protein.
  
     0.729
ACV23931.1
PFAM: Type II secretion system F domain.
  
     0.721
ACV23871.1
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: viral A-type inclusion protein.
  
     0.719
ACV23917.1
PFAM: helix-turn-helix HxlR type; KEGG: ppd:Ppro_1054 HxlR family transcriptional regulator.
  
     0.690
ACV24785.1
TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; KEGG: dol:Dole_0740 CRISPR-associated RAMP Csm5 family protein.
  
     0.662
ACV25034.1
PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: gem:GM21_2431 FG-GAP repeat protein.
  
     0.662
ACV24889.1
KEGG: mxa:MXAN_7399 hypothetical protein.
  
     0.658
ACV24894.1
PFAM: protein of unknown function DUF95 transmembrane; KEGG: RNA methyltransferase, TrmH family protein.
  
     0.619
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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