STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU13138.1KEGG: mea:Mex_p10045 conjugal transfer protein TraA; TIGRFAM: Ti-type conjugative transfer relaxase TraA; PFAM: MobA/MobL protein. (1074 aa)    
Predicted Functional Partners:
ADU11785.1
KEGG: pzu:PHZ_c0200 helicase, UvrD/Rep family; TIGRFAM: double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
  
 
 0.840
ADU13137.1
KEGG: mea:Mex_p10044 hypothetical protein.
       0.741
ADU11706.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.693
ADU14030.1
TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; RQC domain; KEGG: ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase; helicase domain protein.
  
 
 0.606
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.559
ADU13417.1
PFAM: UvrD/REP helicase; KEGG: pzu:PHZ_c2302 DNA helicase II.
  
 
 0.517
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.511
ADU12227.1
PFAM: TRAG family protein; KEGG: ara:Arad_15020 Ti-type conjugative transfer system protein TraG.
 
   
 0.503
ADU13140.1
PFAM: TRAG family protein; KEGG: ara:Arad_15020 Ti-type conjugative transfer system protein TraG.
 
   
 0.491
ADU12167.1
Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Ada metal-binding domain-containing protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; helix-turn-helix- domain containing protein AraC type; KEGG: rpf:Rpic12D_2450 transcriptional regulator, AraC family; SMART: Helix-turn-helix, AraC domain.
     
 0.474
Your Current Organism:
Asticcacaulis excentricus
NCBI taxonomy Id: 573065
Other names: A. excentricus CB 48, Asticcacaulis excentricus ATCC 15261, Asticcacaulis excentricus CB 48, Asticcacaulis excentricus DSM 4724, Asticcacaulis excentricus str. CB 48, Asticcacaulis excentricus strain CB 48
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