node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DMR_27100 | pgm | DMR_27100 | DMR_25390 | Phosphohexose mutase. | Phosphoglucomutase. | 0.971 |
DMR_27100 | prs | DMR_27100 | DMR_29430 | Phosphohexose mutase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.946 |
DMR_27100 | rpiA | DMR_27100 | DMR_44990 | Phosphohexose mutase. | Ribose-5-phosphate isomerase A. | 0.919 |
DMR_27100 | rpiB | DMR_27100 | DMR_21090 | Phosphohexose mutase. | Ribose-5-phosphate isomerase B. | 0.915 |
DMR_27100 | tkt | DMR_27100 | DMR_21080 | Phosphohexose mutase. | Transketolase; Belongs to the transketolase family. | 0.933 |
glyA | glyA-2 | DMR_14920 | DMR_39990 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
glyA | rpiB | DMR_14920 | DMR_21090 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribose-5-phosphate isomerase B. | 0.911 |
glyA | tkt | DMR_14920 | DMR_21080 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transketolase; Belongs to the transketolase family. | 0.487 |
glyA | upp | DMR_14920 | DMR_08390 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.781 |
glyA-2 | glyA | DMR_39990 | DMR_14920 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
glyA-2 | rpiB | DMR_39990 | DMR_21090 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribose-5-phosphate isomerase B. | 0.945 |
glyA-2 | tkt | DMR_39990 | DMR_21080 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transketolase; Belongs to the transketolase family. | 0.487 |
glyA-2 | upp | DMR_39990 | DMR_08390 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.781 |
gnd | rpe | DMR_05560 | DMR_38890 | Putative 6-phosphogluconate dehydrogenase. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.915 |
gnd | rpiA | DMR_05560 | DMR_44990 | Putative 6-phosphogluconate dehydrogenase. | Ribose-5-phosphate isomerase A. | 0.937 |
gnd | rpiB | DMR_05560 | DMR_21090 | Putative 6-phosphogluconate dehydrogenase. | Ribose-5-phosphate isomerase B. | 0.926 |
pgm | DMR_27100 | DMR_25390 | DMR_27100 | Phosphoglucomutase. | Phosphohexose mutase. | 0.971 |
pgm | prs | DMR_25390 | DMR_29430 | Phosphoglucomutase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.915 |
pgm | rpiA | DMR_25390 | DMR_44990 | Phosphoglucomutase. | Ribose-5-phosphate isomerase A. | 0.932 |
pgm | rpiB | DMR_25390 | DMR_21090 | Phosphoglucomutase. | Ribose-5-phosphate isomerase B. | 0.900 |