STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADK79337.1Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: aoe:Clos_0318 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein. (343 aa)    
Predicted Functional Partners:
ADK79338.1
COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: aoe:Clos_0319 transport system permease protein; PFAM: transport system permease protein; SPTR: Transport system permease protein; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.963
ADK79339.1
ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439:IPR017871; KEGG: aoe:Clos_0320 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
 
 
 0.933
ADK79345.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR002750:IPR000878; KEGG: rca:Rcas_0637 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase.
  
  
 0.837
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.806
ADK79344.1
COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878:IPR003043; KEGG: mta:Moth_1092 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase.
     
 0.800
ADK79343.1
COGs: COG2241 Precorrin-6B methylase 1; KEGG: cac:CAC0584 precorrin-6B methylase 1 CobL1/CbiE; SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
     
 0.797
ADK79341.1
Precorrin-8X methylmutase CbiC/CobH; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: scl:sce0238 hypothetical protein; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase.
     
 0.792
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
     
 0.787
ADK79346.1
Cysteine-rich small domain protein; COGs: COG2158 Uncharacterized protein containing a Zn-finger-like domain; InterPro IPR007212; KEGG: dsa:Desal_0255 cysteine-rich small domain protein; PFAM: cysteine-rich small domain; SPTR: Cysteine-rich small domain protein; PFAM: Cysteine-rich small domain.
       0.783
ADK79347.1
COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: drm:Dred_2191 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
       0.781
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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