STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addCOGs: COG1816 Adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: cts:Ctha_0358 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Adenosine deaminase; TIGRFAM: adenosine deaminase; manually curated; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (368 aa)    
Predicted Functional Partners:
ADK83219.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.933
ADK83376.1
COGs: COG1816 Adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: lic:LIC10459 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase.
  
  
 
0.927
ADK79774.1
Metallophosphoesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR018282:IPR006179; KEGG: syp:SYNPCC7002_A0150 Ser/Thr protein phosphatase family protein; PFAM: metallophosphoesterase; SPTR: Ser/Thr protein phosphatase family protein; PFAM: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
    
 0.914
ADK80176.1
COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006146:IPR004843:IPR008334:IPR006179; KEGG: taf:THA_358 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: Protein UshA; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family.
    
 0.914
ADK80393.1
COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: oan:Oant_2761 inosine/uridine-preferring nucleoside hydrolase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: Inosine/uridine-preferring nucleoside hydrolase; PFAM: Inosine-uridine preferring nucleoside hydrolase.
  
 
 0.913
ADK83003.1
COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR015910:IPR001910; KEGG: lba:Lebu_1571 purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: Putative uncharacterized protein; PFAM: Inosine-uridine preferring nucleoside hydrolase.
 
 
 0.913
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.911
ADK79211.1
COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: dge:Dgeo_0101 deoxynucleoside kinase; PFAM: deoxynucleoside kinase; SPTR: Deoxynucleoside kinase; PFAM: Deoxynucleoside kinase.
     
 0.901
ADK81528.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991:IPR001962:IPR001674:IPR017926:IPR 004739; KEGG: aae:aq_236 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; asparagine synthase; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; Asparagine synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
  
  
 0.560
ADK79810.1
Rhamnan synthesis F; COGs: COG3754 Lipopolysaccharide biosynthesis protein; InterPro IPR007739; KEGG: afo:Afer_1971 glycosyl transferase family 2; PFAM: Rhamnan synthesis F; SPTR: Glycosyl transferase family 2; PFAM: Rhamnan synthesis protein F; Phosphoribosyl transferase domain; Protein of unknown function (DUF616).
  
 
 0.553
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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