STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK79960.1Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: sed:SeD_A4225 mandelate racemase/muconate lactonizing enzyme family protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Putative uncharacterized protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain. (396 aa)    
Predicted Functional Partners:
ADK82357.1
Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342:IPR018110; KEGG: dsy:DSY1349 hypothetical protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Putative uncharacterized protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
  
  
 
0.906
ADK79961.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: met:M446_1233 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
       0.777
ADK79959.1
Hypothetical protein.
       0.668
ADK83064.1
Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342:IPR018110; KEGG: dat:HRM2_12000 chloromuconate cycloisomerase-like protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Chloromuconate cycloisomerase-like protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
  
     0.663
ADK80280.1
Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: aoe:Clos_0927 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
  
     0.614
ADK79962.1
Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: rsk:RSKD131_3574 TRAP-T family transporter, large (12 TMs) inner membrane subunit; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative uncharacterized protein; PFAM: Tripartite tricarboxylate transporter TctA family.
       0.606
ADK79963.1
KEGG: tle:Tlet_0634 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Tripartite tricarboxylate transporter TctB family.
       0.559
ADK79964.1
COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: ebr:ECB_03721 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Uncharacterized protein UPF0065; PFAM: Tripartite tricarboxylate transporter family receptor.
  
    0.443
ADK79965.1
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.421
ADK83182.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
 
    0.401
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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