STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK80075.1Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078:IPR003018:IPR002197:IPR003593:IPR 010113:IPR020441; KEGG: rpa:RPA1374 sigma-54 dependent, vanadium nitrogenase transcriptional regulator, VnfA; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Sigma-54 dependent, Vanadium nitrogenase transcriptional regulator, VnfA; TIGRFAM: Nif-specific regulatory protein; PFAM: GAF [...] (515 aa)    
Predicted Functional Partners:
ADK81179.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR020441:IPR003018:IPR003593:IPR002078:IPR 002197; KEGG: tde:TDE2079 sigma-54 dependent transcriptional regulator, putative; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Sigma-54 dependent transcriptional regulator, putative; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
  
  
 
0.912
ADK82111.1
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR003018:IPR002078:IPR002197:IPR020441:IPR 003593; KEGG: cts:Ctha_1655 transcriptional regulator, NifA, fis family; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA, Fis Family; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulat [...]
  
  
 
0.904
ADK83130.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: lbl:LBL_1670 DNA-directed RNA polymerase sigma-54 subunit; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase sigma-54 subunit; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; manually curated; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.808
ADK82438.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR005467:IPR 004358:IPR013767; KEGG: dal:Dalk_1499 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS [...]
 
 
 
 0.734
ADK80074.1
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
       0.693
ADK80740.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR004358:IPR013656:IPR003661:IPR 003594:IPR005467:IPR000700; KEGG: rba:RB3779 putative histidine protein kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacc [...]
 
 
 
 0.637
ADK80428.1
COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR017900:IPR017871:IPR001450:IPR004108:IPR 007202:IPR017896; KEGG: sfu:Sfum_1846 putative PAS/PAC sensor protein; PFAM: hydrogenase large subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster.
 
      0.626
ADK80953.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR004358:IPR001789:IPR013767:IPR 003661:IPR003594:IPR005467:IPR000700; KEGG: sfu:Sfum_3112 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kina [...]
  
 
 0.577
ADK80576.1
COGs: COG2200 FOG: EAL domain; InterProIPR001789:IPR013767:IPR000160:IPR001633:IPR 000014; KEGG: tgr:Tgr7_1990 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain; GGDEF domain [...]
  
 
 0.537
ADK80546.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000834:IPR004358:IPR003660:IPR013767:IPR 003661:IPR003594:IPR001789:IPR000014:IPR005467; KEGG: dal:Dalk_1692 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS s [...]
 
 
 
 0.521
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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