STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK80203.1CRISPR-associated protein Cas5 family; InterPro IPR010155:IPR013422; KEGG: xac:XAC3838 hypothetical protein; PFAM: CRISPR-associated protein CT1134; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Dvulg subtype; CRISPR-associated protein Cas5, N-terminal domain. (220 aa)    
Predicted Functional Partners:
ADK80204.1
InterPro IPR010144; KEGG: dvu:DVUA0131 CRISPR-associated Csd1 family protein; PFAM: CRISPR-associated protein CT1133; SPTR: CRISPR-associated protein, CT1133 family; TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein, Csd1 family.
 
 
 
 0.988
ADK80205.1
CRISPR-associated protein, Csd2 family; COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482:IPR013418; KEGG: msu:MS0986 hypothetical protein; PFAM: CRISPR-associated protein TM1801; SPTR: CRISPR-associated protein, Csd2 family; TIGRFAM: CRISPR-associated protein, Csd2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family.
 
 
 
 0.988
ADK80202.1
CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterProIPR014021:IPR001650:IPR014001:IPR006483:IPR 006474; KEGG: dma:DMR_14350 hypothetical protein; SMART: DEAD-like helicase; SPTR: Metal dependent phosphohydrolase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3.
   
 0.983
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.935
ADK80206.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.930
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.927
ADK80201.1
Regulatory protein, DeoR; COGs: COG2378 transcriptional regulator protein; KEGG: rca:Rcas_1009 regulatory protein, DeoR; SPTR: Regulatory protein, DeoR; PFAM: HTH domain.
       0.511
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.