STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK80377.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: aba:Acid345_3062 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (563 aa)    
Predicted Functional Partners:
ADK80378.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: sus:Acid_1101 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.968
ADK81341.1
Histidine kinase; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR004358:IPR003661:IPR003594:IPR005467:IPR 000700; KEGG: geo:Geob_1250 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 
 0.880
ADK82281.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ava:Ava_2150 response regulator receiver signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain.
 
 
 0.869
ADK81865.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: chl:Chy400_4163 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.868
ADK83074.1
COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: hoh:Hoch_6548 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
 
 0.868
ADK80183.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: jan:Jann_0536 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.867
ADK80912.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cbi:CLJ_B2758 putative phosphate regulon DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Putative phosphate regulon DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.867
ADK80824.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dol:Dole_1930 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.866
ADK82934.1
COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR011495; KEGG: dma:DMR_10920 two-component hybrid sensor and regulator; PFAM: response regulator receiver; histidine kinase dimerisation/phosphoacceptor; SMART: response regulator receiver; SPTR: Two-component hybrid sensor and regulator; PFAM: Histidine kinase; Response regulator receiver domain.
 
 
 0.866
ADK83040.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: tma:TM1655 response regulator DrrA; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Response regulator DrrA; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.866
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.