STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADK80506.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003661:IPR003594:IPR001789:IPR 005467; KEGG: fno:Fnod_1277 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (727 aa)    
Predicted Functional Partners:
ADK79315.1
Hpt protein; InterPro IPR008207; KEGG: srm:SRM_02645 conserved hypothetical protein containing Hpt domain; PFAM: Hpt domain protein; SPTR: Probable sensor/response hybrid, putative; PFAM: Hpt domain.
  
 0.957
ADK80505.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: eel:EUBELI_01503 two-component system, OmpR family, phosphate regulon response regulator OmpR; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.942
ADK83074.1
COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: hoh:Hoch_6548 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
 0.933
ADK80538.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR001789:IPR003018:IPR003594:IPR 005467; KEGG: glo:Glov_0071 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
 0.920
ADK82281.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ava:Ava_2150 response regulator receiver signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain.
 
 0.908
ADK83090.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR005467:IPR000700:IPR004358; KEGG: dvl:Dvul_0331 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: P [...]
 
 
0.908
ADK82438.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR005467:IPR 004358:IPR013767; KEGG: dal:Dalk_1499 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS [...]
 
 
0.907
ADK81346.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003661:IPR003594:IPR 013767:IPR005467; KEGG: cpo:COPRO5265_0030 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFA [...]
 
 0.897
ADK79624.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013767:IPR008207:IPR005467:IPR000700; KEGG: dma:DMR_25470 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Sensor protein; TIGRFAM: PAS [...]
 
 
0.896
ADK80016.1
COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR000014:IPR 001610:IPR005467:IPR000700; KEGG: ote:Oter_0386 multi-sensor hybrid histidine kinase; PFAM: PAS fold-3 domain protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.891
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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