STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK80585.1Peptidoglycan glycosyltransferase; COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterPro IPR001264:IPR001460; KEGG: npu:Npun_R3281 penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1C; manually curated; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1C. (765 aa)    
Predicted Functional Partners:
ADK80584.1
COGs: COG2373 Large extracellular alpha-helical protein; InterPro IPR002890:IPR011625:IPR001599; KEGG: scl:sce4409 hypothetical protein; PFAM: alpha-2-macroglobulin domain protein 2; alpha-2-macroglobulin domain protein; alpha-2-macroglobulin; SPTR: Alpha-2-macroglobulin family N-region; PFAM: MG2 domain; Alpha-2-macroglobulin family; Alpha-2-macroglobulin MG1 domain; Alpha-2-macroglobulin family N-terminal region.
 
   
 0.960
ADK80854.1
Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR011816:IPR001264:IPR001460; KEGG: bre:BRE_738 penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
  
  
0.935
ADK80583.1
KEGG: hoh:Hoch_5250 protein of unknown function DUF1707; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2154); Domain of unknown function (DUF1707).
       0.658
ADK81736.1
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: tde:TDE2753 LysM/M23/M37 peptidase; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: LysM domain/M23/M37 peptidase domain protein; PFAM: Peptidase family M23; LysM domain.
  
     0.596
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.572
ADK81194.1
Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: tpa:TP0500 penicillin-binding protein (pbp-1); PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein (Pbp-1); TIGRFAM: penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
  
   
 0.566
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
   
 0.558
ADK82288.1
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tde:TDE0110 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; PFAM: Peptidase family M23.
  
     0.545
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
   
 0.522
ADK80857.1
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047; KEGG: tde:TDE1738 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SPTR: M23/M37 peptidase domain protein; PFAM: Peptidase family M23.
  
     0.514
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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