STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (274 aa)    
Predicted Functional Partners:
ADK80775.1
YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tde:TDE1908 hypothetical protein; PFAM: YbbR family protein; SPTR: Putative uncharacterized protein; PFAM: YbbR-like protein.
 
  
 0.981
acpS
Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
     
 0.816
ADK80777.1
Protein of unknown function DUF2225; COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: tde:TDE2274 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2225).
       0.808
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
     
 0.773
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
     
 0.767
ADK80779.1
Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005273:IPR005122; KEGG: tde:TDE2491 DNA polymerase domain-containing protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: DNA polymerase domain protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
       0.758
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.683
ADK80773.1
Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
     
 0.624
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
     
 0.615
ADK80783.1
PASTA domain containing protein; COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: tde:TDE1643 PASTA domain-containing protein; PFAM: PASTA domain containing protein; SMART: PASTA domain containing protein; SPTR: Pasta domain protein; PFAM: PASTA domain.
     
 0.603
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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