node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADK79366.1 | ADK80863.1 | Spirs_0209 | Spirs_1736 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001440:IPR013105:IPR019734:IPR 013026; KEGG: bhy:BHWA1_00483 cAMP-binding protein; PFAM: cyclic nucleotide-binding; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SPTR: Cyclic nucleotide-binding protein with tetratricopeptide repeat; PFAM: Cyclic nucleotide-binding domain. | 0.414 |
ADK79366.1 | ADK80864.1 | Spirs_0209 | Spirs_1737 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR002373:IPR000595:IPR018488; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain. | 0.812 |
ADK79366.1 | ADK82213.1 | Spirs_0209 | Spirs_3115 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR002373:IPR018488; KEGG: tde:TDE2437 cyclic nucleotide binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding domain protein; PFAM: Cyclic nucleotide-binding domain. | 0.854 |
ADK79366.1 | ADK82800.1 | Spirs_0209 | Spirs_3714 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018488:IPR000595:IPR002373; KEGG: mxa:MXAN_2702 cyclic nucleotide-binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding domain protein; PFAM: Cyclic nucleotide-binding domain. | 0.831 |
ADK79366.1 | ADK83108.1 | Spirs_0209 | Spirs_4024 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. | Cyclic nucleotide modulated signal transduction histidine kinase; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR003594:IPR000595; KEGG: tde:TDE0102 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ATP-binding region ATPase domain protein; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Cyclic nucleotide-binding domain. | 0.647 |
ADK79437.1 | ADK80860.1 | Spirs_0281 | Spirs_1733 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | Mammalian cell entry related domain protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein. | 0.404 |
ADK79437.1 | ADK80863.1 | Spirs_0281 | Spirs_1736 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001440:IPR013105:IPR019734:IPR 013026; KEGG: bhy:BHWA1_00483 cAMP-binding protein; PFAM: cyclic nucleotide-binding; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SPTR: Cyclic nucleotide-binding protein with tetratricopeptide repeat; PFAM: Cyclic nucleotide-binding domain. | 0.516 |
ADK79437.1 | ADK80864.1 | Spirs_0281 | Spirs_1737 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR002373:IPR000595:IPR018488; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain. | 0.825 |
ADK79437.1 | ADK82213.1 | Spirs_0281 | Spirs_3115 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR002373:IPR018488; KEGG: tde:TDE2437 cyclic nucleotide binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding domain protein; PFAM: Cyclic nucleotide-binding domain. | 0.852 |
ADK79437.1 | ADK82800.1 | Spirs_0281 | Spirs_3714 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018488:IPR000595:IPR002373; KEGG: mxa:MXAN_2702 cyclic nucleotide-binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding domain protein; PFAM: Cyclic nucleotide-binding domain. | 0.819 |
ADK79437.1 | ADK83108.1 | Spirs_0281 | Spirs_4024 | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | Cyclic nucleotide modulated signal transduction histidine kinase; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR003594:IPR000595; KEGG: tde:TDE0102 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ATP-binding region ATPase domain protein; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Cyclic nucleotide-binding domain. | 0.769 |
ADK80852.1 | ADK80863.1 | Spirs_1725 | Spirs_1736 | P83100 family protein; InterPro IPR007926; KEGG: tde:TDE2699 antigen, putative; PFAM: P83100 family protein; SPTR: Antigen, putative; PFAM: Borrelia P83/100 protein. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001440:IPR013105:IPR019734:IPR 013026; KEGG: bhy:BHWA1_00483 cAMP-binding protein; PFAM: cyclic nucleotide-binding; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SPTR: Cyclic nucleotide-binding protein with tetratricopeptide repeat; PFAM: Cyclic nucleotide-binding domain. | 0.812 |
ADK80852.1 | ADK80864.1 | Spirs_1725 | Spirs_1737 | P83100 family protein; InterPro IPR007926; KEGG: tde:TDE2699 antigen, putative; PFAM: P83100 family protein; SPTR: Antigen, putative; PFAM: Borrelia P83/100 protein. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR002373:IPR000595:IPR018488; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain. | 0.601 |
ADK80852.1 | ADK81181.1 | Spirs_1725 | Spirs_2059 | P83100 family protein; InterPro IPR007926; KEGG: tde:TDE2699 antigen, putative; PFAM: P83100 family protein; SPTR: Antigen, putative; PFAM: Borrelia P83/100 protein. | Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: lic:LIC10862 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. | 0.410 |
ADK80852.1 | ADK83108.1 | Spirs_1725 | Spirs_4024 | P83100 family protein; InterPro IPR007926; KEGG: tde:TDE2699 antigen, putative; PFAM: P83100 family protein; SPTR: Antigen, putative; PFAM: Borrelia P83/100 protein. | Cyclic nucleotide modulated signal transduction histidine kinase; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR003594:IPR000595; KEGG: tde:TDE0102 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ATP-binding region ATPase domain protein; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Cyclic nucleotide-binding domain. | 0.606 |
ADK80860.1 | ADK79437.1 | Spirs_1733 | Spirs_0281 | Mammalian cell entry related domain protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein. | COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box. | 0.404 |
ADK80860.1 | ADK80863.1 | Spirs_1733 | Spirs_1736 | Mammalian cell entry related domain protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001440:IPR013105:IPR019734:IPR 013026; KEGG: bhy:BHWA1_00483 cAMP-binding protein; PFAM: cyclic nucleotide-binding; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SPTR: Cyclic nucleotide-binding protein with tetratricopeptide repeat; PFAM: Cyclic nucleotide-binding domain. | 0.648 |
ADK80860.1 | ADK80864.1 | Spirs_1733 | Spirs_1737 | Mammalian cell entry related domain protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein. | Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR002373:IPR000595:IPR018488; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain. | 0.602 |
ADK80860.1 | ADK81181.1 | Spirs_1733 | Spirs_2059 | Mammalian cell entry related domain protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein. | Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: lic:LIC10862 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. | 0.633 |
ADK80860.1 | ADK82884.1 | Spirs_1733 | Spirs_3798 | Mammalian cell entry related domain protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein. | Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001901:IPR001054:IPR007890; KEGG: tde:TDE0932 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase catalytic domain protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. | 0.714 |