STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK81161.1COGs: COG1413 FOG: HEAT repeat; InterPro IPR004155; KEGG: tde:TDE0437 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT-like repeat domain protein; PFAM: PBS lyase HEAT-like repeat; HEAT repeat. (460 aa)    
Predicted Functional Partners:
ADK81157.1
Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: tde:TDE1043 hypothetical protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Membrane protein, putative; PFAM: Predicted permease YjgP/YjgQ family.
 
     0.811
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
       0.808
murJ
Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
       0.805
ADK81158.1
Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: tde:TDE1044 hypothetical protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Membrane protein, putative; PFAM: Predicted permease YjgP/YjgQ family.
 
     0.801
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
    0.780
ADK82242.1
Tetratricopeptide TPR_2 repeat protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR013026:IPR001440:IPR013105; KEGG: bdu:BDU_193 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat.
 
 
   0.747
ADK79438.1
PBS lyase HEAT domain protein repeat-containing protein; COGs: COG1413 FOG: HEAT repeat; InterPro IPR004155; KEGG: ter:Tery_1841 peptidase C14, caspase catalytic subunit P20; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: Peptidase C14, caspase catalytic subunit p20.
  
     0.746
ADK80642.1
TPR repeat-containing protein; InterPro IPR001440:IPR019734:IPR013026; KEGG: tde:TDE1887 TPR domain-containing protein; PFAM: TPR repeat-containing protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat.
 
     0.728
ADK81975.1
WD40 repeat, subgroup; InterProIPR019781:IPR019782:IPR017986:IPR001680:IPR 019775; KEGG: tde:TDE2184 hypothetical protein; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat protein; SPTR: Putative uncharacterized protein; PFAM: WD domain, G-beta repeat.
 
  
 0.708
ADK82913.1
Restriction endonuclease; InterProIPR019734:IPR013105:IPR001440:IPR007560:IPR 013026; KEGG: tpp:TPASS_0915 hypothetical protein; PFAM: restriction endonuclease; Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; PFAM: Restriction endonuclease.
 
     0.705
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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