node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADK80676.1 | ADK80677.1 | Spirs_1549 | Spirs_1550 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | 0.962 |
ADK80676.1 | ddl | Spirs_1549 | Spirs_2895 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.756 |
ADK80676.1 | mraY | Spirs_1549 | Spirs_1548 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.976 |
ADK80676.1 | murB | Spirs_1549 | Spirs_2155 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.551 |
ADK80676.1 | murC | Spirs_1549 | Spirs_2282 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.916 |
ADK80676.1 | murD | Spirs_1549 | Spirs_2887 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.891 |
ADK80676.1 | murE | Spirs_1549 | Spirs_2893 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.776 |
ADK80676.1 | murF | Spirs_1549 | Spirs_1547 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.968 |
ADK80676.1 | murG | Spirs_1549 | Spirs_1705 | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.975 |
ADK80677.1 | ADK80676.1 | Spirs_1550 | Spirs_1549 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | 0.962 |
ADK80677.1 | ddl | Spirs_1550 | Spirs_2895 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.896 |
ADK80677.1 | mraY | Spirs_1550 | Spirs_1548 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.893 |
ADK80677.1 | murB | Spirs_1550 | Spirs_2155 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.727 |
ADK80677.1 | murC | Spirs_1550 | Spirs_2282 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.912 |
ADK80677.1 | murD | Spirs_1550 | Spirs_2887 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.915 |
ADK80677.1 | murE | Spirs_1550 | Spirs_2893 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.709 |
ADK80677.1 | murF | Spirs_1550 | Spirs_1547 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.940 |
ADK80677.1 | murG | Spirs_1550 | Spirs_1705 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.933 |
ADK80677.1 | rodA | Spirs_1550 | Spirs_2071 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.847 |
ddl | ADK80676.1 | Spirs_2895 | Spirs_1549 | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | 0.756 |