STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (225 aa)    
Predicted Functional Partners:
ADK81652.1
PTSINtr with GAF domain, PtsP; COGs: COG3605 Signal transduction protein containing GAF and PtsI domains; InterProIPR000121:IPR003018:IPR008731:IPR008279:IPR 006318; KEGG: dat:HRM2_44960 Pdp; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; SMART: GAF domain protein; SPTR: Pdp; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: GAF domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransfe [...]
       0.784
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.780
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.756
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
   
 
 0.704
ADK81496.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: fsu:Fisuc_2273 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; SPTR: Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.702
rlmE
Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
 
 0.667
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.626
ADK79730.1
Protein of unknown function DUF88; InterPro IPR002790; KEGG: cph:Cpha266_2085 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF88.
  
  
 0.618
ADK82439.1
KEGG: amr:AM1_3453 hypothetical protein; SPTR: Conserved domain protein; PFAM: Protein of unknown function DUF88.
  
  
 0.618
rpmD
COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR018038:IPR000517:IPR005996; KEGG: sss:SSUSC84_0087 50S ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
   
    0.610
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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