STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK81690.1Xylose isomerase domain protein TIM barrel; COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR012307; KEGG: htu:Htur_4472 hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: Hydroxypyruvate isomerase; PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family. (265 aa)    
Predicted Functional Partners:
ADK79655.1
2-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006183:IPR006115:IPR002204:IPR006398; KEGG: dsy:DSY4169 tartronate semialdehyde reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase.
  
 
 0.928
ADK81673.1
2-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR002204:IPR006115:IPR006398:IPR006183; KEGG: dda:Dd703_0845 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase.
  
 
 0.928
ADK81684.1
COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: amt:Amet_2953 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Putative uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
   
 
 0.910
ADK82730.1
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: dal:Dalk_2294 glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Glyoxylate reductase; manually curated; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
   
 
 0.910
ADK81689.1
Inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: bac:BamMC406_1347 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Belongs to the Gfo/Idh/MocA family.
 
    0.842
ADK79884.1
Xylose isomerase domain protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: stm:STM4427 putative endonuclease; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: Putative endonuclease; PFAM: Xylose isomerase-like TIM barrel.
 
     0.598
ADK82728.1
Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: bhy:BHWA1_00789 xylulose kinase; PFAM: Carbohydrate kinase, FGGY-like; PRIAM: Xylulokinase; SPTR: Xylulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain.
     
  0.499
ADK81691.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR013838:IPR000843; KEGG: hor:Hore_14510 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family.
       0.439
ADK79640.1
nucleoside:H symporter; InterPro IPR004740; KEGG: csa:Csal_0765 nucleoside:H+ symporter; PFAM: nucleoside:H symporter; SPTR: Nucleoside:H+ symporter; PFAM: Nucleoside H+ symporter; TIGRFAM: nucleoside transporter.
 
     0.437
ADK81688.1
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR020471; KEGG: str:Sterm_3216 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Putative uncharacterized protein; PFAM: Aldo/keto reductase family.
  
    0.431
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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