STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK81939.1Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dae:Dtox_1189 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family. (456 aa)    
Predicted Functional Partners:
ADK81401.1
Purine or other phosphorylase family 1; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845; KEGG: cff:CFF8240_1515 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; PFAM: purine or other phosphorylase family 1; SPTR: MTA/SAH nucleosidase; PFAM: Phosphorylase superfamily.
    
 0.907
ADK81940.1
COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: tte:TTE1365 metal-dependent hydrolase of the TIM-barrel fold; PFAM: amidohydrolase 2; SPTR: Amidohydrolase family protein; PFAM: Amidohydrolase.
     
 0.782
ADK81936.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterProIPR013027:IPR001450:IPR000103:IPR017896:IPR 017900; KEGG: ckr:CKR_1805 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
       0.693
ADK81935.1
InterPro IPR007419; KEGG: pho:PH1750.1n hypothetical protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain.
     
 0.690
ADK81937.1
InterPro IPR001041; KEGG: ckl:CKL_2061 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.689
ADK81938.1
Amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168:IPR002933:IPR011650:IPR017439; KEGG: sti:Sthe_2535 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: amidohydrolase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase.
       0.689
ADK81947.1
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: cwo:Cwoe_2778 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
  
 0.596
ADK81945.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: sti:Sthe_0592 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Putative uncharacterized protein; PFAM: FAD dependent oxidoreductase.
     
 0.592
ADK81946.1
COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: cac:CAC3337 amidohodrolase; PFAM: amidohydrolase 2; SPTR: Predicted amidohodrolase (Dihydroorotase family); PFAM: Amidohydrolase.
     
 0.591
ADK81941.1
KEGG: cyt:cce_1529 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1393).
       0.576
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
Server load: low (14%) [HD]