STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK81945.1FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: sti:Sthe_0592 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Putative uncharacterized protein; PFAM: FAD dependent oxidoreductase. (400 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 
 0.976
ADK81936.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterProIPR013027:IPR001450:IPR000103:IPR017896:IPR 017900; KEGG: ckr:CKR_1805 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
  
 0.972
ADK82082.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR001450:IPR017896:IPR017900; KEGG: tai:Taci_0971 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
   
 0.950
ADK82081.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR007419:IPR006076; KEGG: acp:A2cp1_1475 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase.
  
  
 
0.926
ADK83025.1
COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: bhy:BHWA1_00425 L-allo-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Threonine aldolase; PFAM: Beta-eliminating lyase.
 
  
 0.923
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.920
gcvPB
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
 
 0.915
gcvPA
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
   
 
 0.909
ADK81937.1
InterPro IPR001041; KEGG: ckl:CKL_2061 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.895
ADK81935.1
InterPro IPR007419; KEGG: pho:PH1750.1n hypothetical protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain.
 
    0.885
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
Server load: low (28%) [ZH]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.