STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK82100.1Patatin; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: ppu:PP_4514 patatin; PFAM: Patatin; SPTR: Putative uncharacterized protein; PFAM: Patatin-like phospholipase. (739 aa)    
Predicted Functional Partners:
ADK82101.1
methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.765
ADK82098.1
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: cts:Ctha_2722 efflux transporter, RND family, MFP subunit; SPTR: Putative uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.549
ADK82099.1
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: ara:Arad_7775 transcriptional regulator protein; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator protein; PFAM: Bacterial regulatory proteins, tetR family.
     
 0.503
ADK80150.1
Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: rrs:RoseRS_3086 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein.
 
     0.426
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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